Superior infection prevention starts with ChloraPrep
ChloraPrep is a rapid-acting, persistent, and broad-spectrum antiseptic for a range of minor and major medical procedures. The 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol formulation acts fast on a broad spectrum of bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), and keeps fighting bacteria for at least 48 hours.1,2 Together, the formulation and applicator provide a proven system that supports infection control guidelines for helping to reduce the incidence of BSIs and SSIs.
The ChloraPrep Advantage
ChloraPrep is a superior broad-spectrum antimicrobial compared to traditional iodophors.
- Rapid acting: The 70% isopropyl alcohol in ChloraPrep rapidly kills microorganisms versus free iodine, which requires two minutes to begin antimicrobial activity3
- Persistent: ChloraPrep maintains antimicrobial activity for at least 48 hours1,2 compared to two hours for free iodine3
- Broad spectrum: ChloraPrep antimicrobial activity is effective against microorganisms including gram-positive and gram-negative bacteria, Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), Clostridium difficile, Acineobacter, and most viruses and fungi2,3,4
- Active in protein-rich biomaterials: Remains active in the presence of blood, serum and other protein-rich biomaterials4,5 unlike traditional iodophors, which are neutralized6
- Low irritation: CHG demonstrates low incidence of irritation4
Learn more about the ChloraPrep advantage
CHG formulations are preferred for patient preoperative skin prep.
Featured Studies
Current Approaches for the Prevention of Surgical Site Infections
- Following a multimodal approach, including use of CHG formulations for patient preoperative skin preparation, can improve patient outcomes and decrease hospital costs related to infections in surgical sites7
Prevention of Perioperative Infection
- Chlorhexidine gluconate is superior to povidone-iodine for preoperative skin antisepsis for the patient8
1 Garcia R, Mulberry G, Brady A, Hibbard JS. Comparison of ChloraPrep and Betadine as preoperative skin preparation antiseptics. Poster presented at: 40th Annual Meeting of the Infectious Disease Society of America; October 25, 2002.
2 Data on file, CareFusion, Inc.
3 Crosby CT, Mares AK. Skin antisepsis: past, present, and future. J Vasc Access Devices. Spring 2001:26-31.
4 Denton GW. Chlorhexidine. In: Block SS. Disinfection, Sterilization, and Preservation. 5th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2001:321-336.
5 Chaiyakunapruk N, Veenstra DL, Lipsky BA, Saint S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. An intern Med. 2002;136:792-801.
6 Gottardi W. Iodine and Iodine Compounds. In: Block SS. Disinfection, Serilization, and Preservation. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001:159-183.
7 Florman S, Nichols RL. Current Approaches for the Prevention of Surgical Site Infections. Am. J. Infect. Dis. 2007;3(1): 51-61.
8 Fletcher N, Sofianos D, Brantling M, Obremskey B and W. Prevention of Perioperative Infection. J Bone Joint Surg AM. 2007;89:1605-1618.
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Learn more about the source of infection – the patient's own skin.
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